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Important Safety Issues With Methylsulfonylmethane and How It Works

Warnings and Precautions With Methylsulfonylmethane

Reasonable doses of methylsulfonylmethane taken by mouth for a limited period of time are probably safe for most people, especially if high-quality supplements are used (since such supplements are less likely to be contaminated or have other problems). Some people may be more likely to experience problems due to the supplement. Therefore, you should talk with your healthcare provider prior to starting treatment if you:
  • Have any chronic or severe health problems
  • Have any allergies, including allergies to foods, dyes, or preservatives.
  • Are pregnant or thinking of becoming pregnant (see MSM and Pregnancy)
  • Are breastfeeding (see MSM and Breastfeeding).
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
(Click Methylsulfonylmethane Safety for more information, including any available warnings and precautions.)

How Does It Work?

The methylsulfonylmethane molecule contains sulfur and is a source for sulfur that the body needs to make certain amino acids. However, most people get plenty of sulfur through eating protein. Researchers think that methylsulfonylmethane might decrease inflammation and may reduce homocysteine levels. High homocysteine levels may increase the risk of heart disease, strokes, and hardening of the arteries (atherosclerosis).

Is Methylsulfonylmethane Effective?

Very early evidence suggests that a combination of methylsulfonylmethane with glucosamine might help with arthritis, but there is little evidence suggesting that the supplement really works for most other uses (see Does MSM Work? for more information).
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