Moduretic Overdose

The effects of a Moduretic overdose will vary, depending on how much of the drug was taken and whether it was taken with any other drugs or alcohol. Symptoms may include increased urination, vomiting, fever, and low blood pressure. Treatment options for a Moduretic overdose also vary; options range from "pumping the stomach" to giving specific medications and fluids.

 

Moduretic Overdose: An Introduction

Moduretic® (amiloride-HCTZ) is a medication used for controlling high blood pressure and treating water retention (edema). The effects of a Moduretic overdose will vary, depending on a number of factors, including how much Moduretic was taken and whether it was taken with any other medicines, alcohol, and/or street drugs.
 
If you happen to overdose on Moduretic, seek immediate medical attention.
 

Symptoms of a Moduretic Overdose

It is not fully known what the effects of a Moduretic overdose may be in humans.
 Based on the overdose effects in animals and based on the way the drug works, overdose symptoms may include:
 
  • Increased urination
  • Nausea or vomiting
  • Weakness
  • Fever
  • Flushed face
  • Low blood pressure
  • High potassium levels, low potassium levels, or other electrolyte imbalances.
     
This may cause signs or symptoms that include:
 
  • Lightheadedness, dizziness, or fainting
  • Decrease in urine output
  • Drowsiness, headache, or back pain
  • Slow or irregular heartbeat
  • Dry mouth
  • Increased thirst
  • Weakness
  • Tiredness
  • Restlessness
  • Seizures
  • Confusion
  • Muscle pain or cramps
  • Nausea or vomiting
  • Loss of consciousness.
     
(Moduretic Overdose Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;