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Guidelines for Moexipril/HCTZ

How Does It Work?

The HCTZ component of the medication is a diuretic ("water pill"). It works by increasing the amount of salt and water the kidneys remove from the blood. This extra salt and water is then passed out through the urine. The removal of salt and water decreases blood volume, resulting in lower blood pressure.
The moexipril component of the drug is an angiotensin-converting enzyme inhibitor, or ACE inhibitor for short. It works by blocking the activity of the angiotensin-converting enzyme (ACE), an enzyme found in the body. One of the actions of ACE is to help make a hormone in the body that constricts (narrows) blood vessels. When ACE is blocked, less of the blood vessel-constricting hormone is made, which causes blood vessels to relax and blood pressure to lower.

When and How to Take This Medication

Some general considerations to keep in mind during treatment with moexipril/HCTZ include the following:
  • Moexipril/HCTZ comes in tablet form. It is usually taken by mouth once daily.
  • Moexipril/HCTZ tablets may be split in half, if needed.
  • This medication may increase urination. Therefore, you may want to take it in the morning to reduce the need to get up in the middle of the night to use the bathroom.
  • Make sure to take moexipril/HCTZ at the same time each day to maintain an even level of the medication in your blood.
  • Moexipril/HCTZ should be taken about one hour before a meal.
  • For this medication to work properly, it must be taken as prescribed.

Storage Information

Moexipril/HCTZ should be stored at room temperature, away from moisture. Keep this and all other medications out of the reach of children.
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Moexipril/HCTZ Medication Information

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