Specific Products That Interfere With Moexipril
The following sections explain in detail the potential interactions that can occur when moexipril is combined with the drugs listed above.
Combining moexipril with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required. Aliskiren and moexipril should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate to severe kidney problems.
Moexipril may increase the risk for potentially serious allopurinol side effects, especially when allopurinol is first started. If you take moexipril and need to start taking allopurinol, your healthcare provider may choose to monitor you more closely for side effects in the first five weeks of treatment.
Taking moexipril within 24 hours of receiving amifostine could cause your blood pressure to lower to unsafe levels. Talk to your healthcare provider about this possible interaction if you receive amifostine treatment.
Angiotensin II Receptor Blockers (ARBs)
Combining moexipril with an ARB may increase the risk for certain side effects, such as high blood potassium, kidney problems, or very low blood pressure. These medications are sometimes used together with appropriate monitoring.
There have been reports of blood cell problems occurring in people who took an angiotensin-converting enzyme inhibitor (ACE inhibitor) with azathioprine. Although reports have not included moexipril specifically, because it is an ACE inhibitor, your healthcare provider may want to monitor you for this interaction if you start moexipril while taking azathioprine.