Drug Interactions With Nicardipine

Cimetidine and cyclosporine can potentially interact with nicardipine. These drug interactions with nicardipine can alter the amounts of the medications in your blood, potentially increasing your risk of side effects. It is important to talk to your healthcare provider (prior to taking nicardipine) about any drug interactions that may apply to your situation.

 

An Overview of Drug Interactions With Nicardipine

Nicardipine hydrochloride (Cardene®) can potentially interact with a few other medicines. Some of these medicines that may lead to nicardipine drug interactions include:
 

Nicardipine Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when nicardipine is combined with any of the drugs listed above.
 
Cimetidine (Tagamet)
Cimetidine may increase the level of nicardipine in your blood, increasing your risk of nicardipine side effects. Your healthcare provider may need to adjust your nicardipine dose or may suggest an alternative to cimetidine.
 
Cyclosporine (Gengraf, Neoral, Sandimmune)
Taking cyclosporine with nicardipine can increase the level of cyclosporine in your blood, increasing your risk of side effects. Your healthcare provider should carefully monitor the level of cyclosporine in you blood, adjusting your dose as necessary.
 

Final Thoughts on Drug Interactions With Nicardipine

It is possible that not every nicardipine drug interaction was discussed in this article.
 Therefore, you should talk with your pharmacist or healthcare provider about drug interactions with nicardipine that may apply to your situation.
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;