More Info on Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide Interactions
Narcotic Pain Relievers
When taking olmesartan medoxomil/amlodipine/hydrochlorothiazide with a narcotic pain reliever, your blood pressure may decrease too much. If you take these medications together, watch for symptoms of low blood pressure, such as dizziness, lightheadedness, or fainting. If you experience these symptoms, contact your healthcare provider. He or she may need to monitor your blood pressure more closely or lower your olmesartan medoxomil/amlodipine/hydrochlorothiazide dose.
Olmesartan medoxomil/amlodipine/hydrochlorothiazide can make you more sensitive to the effects of neuromuscular-blocking medications. If you are taking olmesartan medoxomil/amlodipine/hydrochlorothiazide and need a neuromuscular-blocker, your healthcare provider may need to monitor you more closely or change the dose of the neuromuscular-blocking medication.
Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
Olmesartan medoxomil-amlodipine-HCTZ can interact with NSAIDs in several ways. The combination could cause your blood pressure to increase or may cause swelling (edema), especially if you have congestive heart failure (CHF). If you are elderly, have kidney disease or kidney failure, are taking a diuretic (water pill), or are dehydrated, taking NSAIDs and this medication together may cause kidney failure. Talk to your healthcare provider about this potential drug interaction before taking these medications together.
Other Blood Pressure Medications
Taking olmesartan medoxomil/amlodipine/hydrochlorothiazide in combination with other blood pressure medications may increase your risk of dangerously low blood pressure. If your blood pressure becomes too low, you may become dizzy, lightheaded, or faint. Only take these medications together with your healthcare provider's approval.
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