Drug Interactions With Olmesartan Medoxomil-Hydrochlorothiazide

Interactions With Olmesartan Medoxomil-Hydrochlorothiazide Explained

The following sections explain in detail the potentially negative interactions that can occur whenolmesartan medoxomil-hydrochlorothiazide is combined with any of the drugs listed above.
 
Diuretics
When taking olmesartan medoxomil-hydrochlorothiazide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when olmesartan medoxomil-hydrochlorothiazide is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of olmesartan medoxomil-hydrochlorothiazide, and/or monitor you more closely.
 
Potassium Supplements or Salt Substitutes With Potassium
If you are taking olmesartan medoxomil-hydrochlorothiazide along with a potassium supplement or a salt substitute with potassium, the levels of potassium in your blood may become too high. This can cause serious problems. Talk to your healthcare provider about using potassium and olmesartan medoxomil-hydrochlorothiazide together in your particular situation.
 
Potassium-Sparing Diuretics
If olmesartan medoxomil-hydrochlorothiazide and a potassium-sparing diuretic are taken together, your body may metabolize the drugs differently than intended and/or increase the levels of potassium in your blood. Your healthcare provider may choose to monitor your progress closely to prevent this interaction.
 
Lithium
When olmesartan medoxomil-hydrochlorothiazide and lithium are taken together, your body may metabolize the drugs differently than intended and increase the levels of lithium in the blood. For this reason, lithium is generally not recommended in people taking olmesartan medoxomil-hydrochlorothiazide.
(Drug Interactions With Olmesartan Medoxomil-Hydrochlorothiazide Continued: Page 3)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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