Drug Interactions With Olmesartan Medoxomil-Hydrochlorothiazide

As with any medication, drug interactions with olmesartan medoxomil-hydrochlorothiazide are possible. If combined with other medications, such as narcotics, barbiturates, or oral diabetes medications, your body may metabolize these drugs differently than intended. As a result, your blood pressure may decrease too much or your blood sugar levels may become too high. If drug interactions with olmesartan medoxomil-hydrochlorothiazide are a concern, your healthcare provider may monitor you more closely or adjust your dosages.

 

Drug Interactions With Olmesartan Medoxomil-Hydrochlorothiazide: An Overview

 Olmesartan medoxomil-hydrochlorothiazide (Benicar HCT®) can potentially interact with a number of other medicines. Some of these drug interactions with olmesartan medoxomil-hydrochlorothiazide include:
 
o Amobarbital (Amytal®)
o Butabarbital (Butisol Sodium®)
o Phenobarbital (Luminal®)
o Pentobarbital (Nembutal®)
o Thiopental (Pentothal®)
  • Narcotics, such as codeine, morphine, oxycodone, and hydrocodone
     
  • Cholestyramine (Prevalite®, Questran®, Questran® Light, LoCholest®)
     
  • Colestipol (Colestid®)
     
  • Corticosteroids, such as prednisone, hydrocortisone (Cortef®), and dexamethasone (Decadron®, Dexone®, Hexadrol®)
     
  • Norepinephrine
     
  • Corticotropin (Acthar®)
     
  • Muscle relaxants, such as tubocurarine
     
  • Nonsteroidal anti-inflammatory drugs (NSAIDs), such as:
 
 
(Drug Interactions With Olmesartan Medoxomil-Hydrochlorothiazide Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;