Nefazodone (Serzone)
Nefazodone can increase the level of
Procardia XL in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your
Procardia XL dose.
Protease Inhibitors
Protease inhibitors can increase the level of Procardia XL in your blood, increasing your risk of side effects. Your healthcare provider may need to decrease your Procardia XL dose.
Quinidine
Procardia XL can decrease the level of quinidine in your blood, perhaps making it less effective. Also, quinidine may increase the level of Procardia XL in your blood, increasing your risk of side effects. Your healthcare provider may need to adjust your dose of these medications.
Rifamycin Derivatives
Rifamycin derivatives can greatly reduce the level of Procardia XL in your blood, making it much less effective. It is generally not recommended to combine Procardia XL with rifamycin derivatives.
Certain Seizure Medications
Taking Procardia XL with certain
seizure medications can decrease the level of Procardia XL in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of Procardia XL.
St. John's Wort
St. John's wort can decrease the level of Procardia XL in your blood, perhaps making it less effective. Your healthcare provider may need to increase your dose of Procardia XL.
Tacrolimus (Prograf)
Procardia XL can increase the level of tacrolimus in your blood, increasing your risk of side effects. Your healthcare provider should monitor the level of tacrolimus in your blood and may need to decrease your tacrolimus dosage.
Warfarin (Coumadin, Jantoven)
There have been reports of an interaction between warfarin and Procardia XL. Procardia XL may increase your risk of bleeding while you are taking warfarin. Your healthcare provider may need to monitor you more closely, especially when starting or stopping Procardia XL.