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Common Reactions to Propranolol/HCTZ

Common Side Effects

For many medications, the prescribing information carefully explains the exact percentage of side effects that occurred during clinical trials. However, the prescribing information for almost all older medications, including propranolol/HCTZ, contains only vague information on potential side effects, without exact percentages. Therefore, it can be difficult to know exactly how common some reactions may be.
Based on the potential side effects of the two drugs in propranolol/HCTZ, possible adverse reactions may include but are not limited to:
  • Dizziness
  • A spinning sensation (vertigo)
  • Fatigue
  • A slow heart rate (bradycardia)
  • Headaches
  • Nausea
  • Vomiting
  • A decrease in blood pressure when moving to a standing position, which could cause dizziness or lightheadedness
  • A change in color vision, causing objects to appear more yellow
  • Tingling, pricking, or numbness of the skin
  • Decreased appetite
  • Abdominal (stomach) pain
  • Diarrhea or constipation
  • Breathing problems
  • Increases in blood sugar (hyperglycemia)
  • Weakness
  • Restlessness  
  • High uric acid levels in the blood, which could cause symptoms of gout
  • Insomnia
  • Vivid dreams
  • Short-term memory problems
  • Impotence (erectile dysfunction or ED)
  • Hair loss.

Final Thoughts

You may experience some or none of the side effects listed in this article. Unfortunately, there is no way for your healthcare provider to know beforehand if you will have problems with a medicine that you have never tried.
Therefore, make sure to let your healthcare provider know if you develop any side effects while taking this drug or if something "just does not seem right." While it may not be related to propranolol/HCTZ, your healthcare provider will be able to diagnose and treat the problem.
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