Drug Interactions With Propranolol Sustained-Release

Drug interactions with propranolol sustained-release can cause your blood pressure to decrease too much, increase the levels of certain drugs in your body, and make the medication less effective. Drugs that can potentially interact with propranolol sustained-release include alcohol, phenobarbital, and calcium channel blockers. If drug interactions with propranolol sustained-release are a concern, your healthcare provider may adjust your dosages or monitor you more closely.

 

Drug Interactions With Propranolol Sustained-Release: An Introduction

 Propranolol hydrochloride sustained-release (Inderal LA®) can potentially interact with a number of other medicines. Some of these drug interactions with propranolol sustained-release can include:
 
  • Cimetidine (Tagamet®)
  • Theophylline (Elixophyllin®, Theo-24®, Uniphyl®, TheoCap™, Theochron®)
  • Rifampin (Rifadin®, Rimactane®, Rofact®)
  • Alcohol
  • Phenytoin (Dilantin®, Phenytek™)
  • Phenobarbital (Solfoton®)
  • Lidocaine (Xylocaine®)
  • Aluminum hydroxide gel (Amphojel®).
 
Drug interactions with propranolol sustained-release also include calcium channel blockers, such as:
 
 
Additional drug interactions include the following:
 
There are also medicines that may interact with the immediate-release form of propranolol sustained-release (Inderal®). You can learn about these by clicking Inderal Drug Interactions. Also, whenever you start a new medicine, make sure to talk with your healthcare provider about possible drug interactions with your current medicines.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;