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Are There Risks With Propranolol Sustained-Release?

Specific Precautions and Warnings With Propranolol Sustained-Release

Some propranolol sustained-release warnings and precautions to be aware of include the following:
  • Propranolol sustained-release can interact with certain medications (see Drug Interactions With Propranolol Sustained-Release).
  • Serious allergic reactions have occurred in people taking propranolol sustained-release. Make sure to discuss this risk with your healthcare provider. Also, seek emergency medical attention if you notice things such as:
    • Hives
    • An unexplained rash or peeling of the skin
    • Difficulty breathing
    • Wheezing
    • Swelling of the face or throat.
  • This medication may hide certain signs of hyperthyroidism. Do not stop treatment suddenly, as this can cause serious symptoms. Make sure to talk with your healthcare provider before stopping propranolol sustained-release so that it can be done in a safe manner.
  • Propranolol sustained-release may cause extreme low blood pressure and/or a slow heart rate in some people. Symptoms can include dizziness, lightheadedness, and fainting. If you develop any of these symptoms, contact your healthcare provider. Extreme low blood pressure is more likely to occur in people who are taking a diuretic, who are on dialysis, or who have diarrhea or vomiting. Also, make sure not to drive, operate any heavy machinery, or perform any other tasks that require alertness before you know how this medicine affects you.
  • People who have severe congestive heart failure and are taking propranolol sustained-release are at an increased risk of making their heart failure worse. Therefore, if you have severe congestive heart failure and your healthcare provider prescribes this drug, it is because he or she believes its benefits outweigh the potential risks. Your doctor may choose to monitor your situation more closely if this is the case.
  • Using beta blockers, such as propranolol sustained-release, for a long time can sometimes lead to heart failure, especially in people with a history of this condition. Contact your healthcare provider if you notice any of the following symptoms:
  • You should not abruptly stop taking propranolol sustained-release. In clinical studies, this has been shown to increase a person's chances for developing angina (chest pain), a heart attack, or serious irregular heart rhythms (arrhythmias). This risk is even greater in people with existing heart disease.
  • Low blood sugar levels have been reported in people taking propranolol sustained-release. This has been more common in infants, children, and people with kidney disease. It has also been more common during fasting, before surgery, or after prolonged exercise. Low blood sugar symptoms may include irritability, trembling, cold sweats, or blurry vision, to name a few (see Inderal and Low Blood Sugar).
  • If you have kidney disease or kidney failure, your body may metabolize the medicine differently than intended. Therefore, your healthcare provider will monitor your situation more closely.
  • Beta blockers are used with caution, if at all, in people with certain lung diseases, such as asthma, emphysema, chronic bronchitis, or COPD. This is because beta blockers affect the lungs and can cause a narrowing of the airways. This risk is increased in people with certain lung diseases. If you develop problems with breathing or wheezing, call your healthcare provider.
  • If you have allergies, taking propranolol sustained-release may increase your reaction to the specific allergens, and your body may not respond to the usual doses of epinephrine.
  • This medication may lower the pressure within the eye (intraocular pressure). This can affect the results of the glaucoma screening test. Stopping propranolol sustained-release will usually increase the intraocular pressure again.
  • If you are going to have surgery, let your healthcare provider or dentist know that you are taking propranolol sustained-release.
  • Propranolol sustained-release is a pregnancy Category C medicine, which means there may be an increased risk to the fetus if you take the drug during pregnancy. Let your healthcare provider know if you are pregnant or thinking of becoming pregnant. If you become pregnant while taking this drug, contact your healthcare provider (see Inderal LA and Pregnancy).
  • Propranolol sustained-release is known to pass through breast milk. Therefore, if you are breastfeeding, be sure to check with your healthcare provider before taking this medication (see Inderal LA and Breastfeeding).  
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Propranolol Sustained-Release Drug Info

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