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Detailed Information on Products That Interfere With Quinapril-Hydrochlorothiazide

Bile Acid Sequestrants
Bile acid sequestrants can bind to quinapril-hydrochlorothiazide in the digestive tract and decrease its absorption into the body. To avoid this drug interaction, quinapril-hydrochlorothiazide should be taken at least one hour before or four to six hours after a bile acid sequestrant has been given.
 
Corticosteroids
Taking corticosteroids with quinapril-hydrochlorothiazide may cause an electrolyte imbalance, especially with the levels of potassium in the blood. If you are taking a corticosteroid with quinapril-hydrochlorothiazide, your healthcare provider may monitor you more closely and/or adjust your dose of medicine as needed.
 
Diabetes Medications
Taking a diabetes medication with quinapril-hydrochlorothiazide may increase blood sugar levels. For your particular situation, your healthcare provider may monitor you more closely and/or adjust your dose of diabetes medications as needed.
 
Diuretics
When taking quinapril-hydrochlorothiazide with a diuretic, your blood pressure may decrease too much. This is more likely to occur when quinapril-hydrochlorothiazide is first started. In order to decrease the chances of this interaction, your healthcare provider may change the dose of either medicine, start you on a lower dose of quinapril-hydrochlorothiazide, and/or monitor you more closely.
 
Injectable Gold
Reactions have been reported in people taking quinapril-hydrochlorothiazide who received gold injections. These reactions included symptoms such as facial flushing, nausea, vomiting, and low blood pressure.
 
Lithium
Quinapril-hydrochlorothiazide may increase the risk of lithium toxicity and may increase the lithium levels in the blood. Your healthcare provider may choose to monitor your blood lithium levels more frequently and may need to adjust your lithium dosage.
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