Drug Interactions With Quinapril-Hydrochlorothiazide

When various medications are taken together, there is a risk of developing drug interactions. With quinapril-hydrochlorothiazide, these interactions may lead to decreased effectiveness of the drugs, extremely low blood pressure, or increased blood sugar levels. Medicines that may potentially cause drug interactions with quinapril-hydrochlorothiazide include cholestyramine, potassium supplements, and nonsteroidal anti-inflammatory drugs, among others.

Quinapril-Hydrochlorothiazide Drug Interactions: An Introduction

 Quinapril-hydrochlorothiazide (sold under the brand name Accuretic® and also sold generically as Quinaretic™) can potentially interact with a number of other medicines. Some of these quinapril-hydrochlorothiazide drug interactions can include:
 
  • Alcohol
  • Barbiturates, such as:
 
    • Amobarbital (Amytal®)
    • Butabarbital (Butisol Sodium®)
    • Phenobarbital (Luminal®)
    • Primidone (Mysoline®)
    • Pentobarbital (Nembutal®)
    • Thiopental (Pentothal®)
 
 
 
  
  • Narcotics, such as codeine, morphine, oxycodone, and hydrocodone
  • Potassium-containing products, such as:
     
    • Potassium chloride (K-Dur®, Klor-Con®, Micro-K®)
    • Potassium citrate (Urocit-K®, Polycitra-K®)
    • Potassium gluconate
    • Potassium phosphate (Neutra-Phos-K®, K-Phos®)
    • Salt substitutes (used to flavor food)
 
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD
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