Sectral

Sectral is a medication often prescribed for the treatment of high blood pressure and certain irregular heart rhythms. It comes in capsule form and is typically taken once or twice a day. The drug works by blocking beta receptors and suppressing certain irregular heart beats that originate in the wrong part of the heart. Potential side effects include fatigue, headaches, and dizziness.

What Is Sectral?

Sectral® (acebutolol hydrochloride) is a prescription medication approved to treat the following conditions:
 
(Click Sectral Uses for more information on what the medication is used for, including possible off-label uses.)
 

Who Makes It?

Brand-name Sectral is made by Mova Pharmaceutical Corporation for Reddy Pharmaceuticals, LLC. Generic versions are made by various manufacturers.
 

How Does It Work?

Sectral belongs to a group of drugs called beta-adrenergic blocking agents, more often known as
 beta blockers. As the name implies, these medications block beta receptors in the body. In addition to blocking beta receptors, however, Sectral also very slightly stimulates the beta receptors. Only a few beta blockers do this; this slight stimulatory action is known as "intrinsic sympathomimetic activity," or ISA.
 
Beta receptors are located in a number of places within the body, including the heart and blood vessels. Stress hormones (such as adrenaline) bind to these receptors and cause certain reactions in the body, such as:
 
By blocking beta receptors, Sectral causes the reverse effect of stress hormones and reduces blood pressure. It also suppresses certain irregular heartbeats that originate in the wrong part of the heart (known specifically as premature ventricular contractions or PVCs).
 
It is also important to note that Sectral is more likely to block beta-1 receptors (such as those in the heart), opposed to beta-2 receptors (such as those found in the lungs). In theory, this may make the medication safer than other beta blockers for people with breathing problems such as asthma.
 

When and How to Take Sectral

Some general considerations include the following:
 
  • Sectral comes in capsule form. It is usually taken by mouth once or twice a day.
     
  • You can take this medication either with a meal or on an empty stomach.
     
  • For the medication to work properly, it must be taken as prescribed. Sectral will not work if you stop taking it.
     
  • In general, this medication should not be stopped suddenly, as serious problems (including heart attacks) may result.
     

Dosing Information

The dose that your healthcare provider recommends will vary depending on a number of factors, including:
 
  • The medical condition being treated
  • Your age
  • How you respond to the medication
  • Other medications you are taking
  • Other medical conditions you may have.
     
As always, do not adjust your dose unless your healthcare provider specifically instructs you to do so.
 
(Click Sectral Dosage for more information.)
 

Side Effects of Sectral

As with any medicine, Sectral may cause side effects. However, not everyone who takes the drug will experience side effects (most people actually tolerate it quite well). If side effects do occur, in most cases, they are minor and either require no treatment or can easily be treated by you or your healthcare provider. Serious side effects are less common.
 
Some of the most common side effects include, but are not limited to:
 
(Click Sectral Side Effects to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
 

Potential Drug Interactions

Sectral can potentially interact with a number of other medications (see Sectral Interactions).
 

What Should I Tell My Healthcare Provider Before Using Sectral?

You should talk with your healthcare provider prior to taking Sectral if you have:
 
  • Peripheral artery disease (PAD)
  • Mesenteric vascular disease (problems with the blood vessels of the intestines)
  • Liver disease, such as liver failure, cirrhosis, or hepatitis
  • Kidney disease, such as kidney failure (renal failure)
  • Diabetes
  • Chest pain (angina)
  • Heart failure
  • A slow heart rate (bradycardia)
  • Asthma
  • Chronic obstructive pulmonary disease (COPD)
  • Hyperthyroidism
  • An upcoming surgery
  • Any allergies, including allergies to food, dyes, or preservatives.
     
Also, let your healthcare provider know if you are:
 
Make sure to tell your healthcare provider about all other medicines you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.
 
(Click Sectral Warnings and Precautions to learn more, including information on who should not take the drug.)
 

Overdose Information

An overdose is likely to cause dangerously low blood pressure (hypotension), a slow heart rate (bradycardia), and other serious problems. If you happen to overdose on Sectral, seek medical attention immediately.
 
(Click Acebutolol Overdose for more information.)
 

What Should I Do If I Miss a Dose of Sectral?

If you forget to take your dose, take the missed dose as soon as your remember. However, if it is almost time for your next dose, simply skip the missed dose and continue with your regular schedule. Do not take a double dose.
 

Available Strengths

Sectral capsules come in the following strengths:
 
  • Sectral 200 mg
  • Sectral 400 mg.
     

Is There a Generic Version of Sectral?

This medication is available in generic form.
 
(Click Generic Sectral for more information.)
 
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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