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Who Should Avoid Spironolactone-HCTZ?

Who Should Not Take Spironolactone-HCTZ?

You should not take spironolactone-HCTZ if you:
  • Are allergic to spironolactone, hydrochlorothiazide, or any inactive component used to make the medication. Your healthcare provider or pharmacist has a list of the inactive ingredients.
  • Have severe kidney disease, including acute kidney failure (renal failure).
  • Are not producing any urine (called "anuria").
  • Have high potassium levels (hyperkalemia) before starting spironolactone-HCTZ.
  • Are allergic to sulfonamides ("sulfa" drugs).
  • You are taking eplerenone (Inspra®).

Precautions and Warnings With Spironolactone-HCTZ: Final Thoughts

There are a number of situations in which spironolactone-HCTZ should not be taken, as well as a number of warnings and precautions people should be aware of before starting the medicine. However, it is possible that not all of the warnings or precautions were discussed in this article. Therefore, you should talk with your healthcare provider about the precautions and warnings with spironolactone-HCTZ that may apply to you.
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