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Tekturna HCT Warnings and Precautions

To help minimize potential risks, talk to your healthcare provider about Tekturna HCT warnings and precautions. This includes potential drug interactions, allergic reactions, and the risk of developing certain side effects. Tekturna HCT warnings and precautions also apply to people who have certain health conditions, such as kidney disease, gout, or diabetes.

Tekturna HCT: What Should I Tell My Healthcare Provider?

You should talk with your healthcare provider prior to taking Tekturna HCT® (aliskiren-HCTZ) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about all other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Tekturna HCT Warnings and Precautions

Warnings and precautions to be aware of prior to taking Tekturna HCT include the following:
  • Pregnant women should not take Tekturna HCT. This drug is a renin inhibitor, and medications that affect the renin-angiotensin system have been shown to cause serious problems when used during pregnancy (see Tekturna HCT and Pregnancy).
  • Tekturna HCT can cause angioedema, a life-threatening reaction that causes swelling of the lips, mouth, tongue, or throat. If you experience such symptoms, seek immediate medical attention.
  • As with all blood pressure medications, Tekturna HCT can cause low blood pressure (hypotension). Let your healthcare provider know if you develop signs of low blood pressure, such as dizziness, lightheadedness, or fainting.
  • Make sure your healthcare provider knows if you have kidney problems before you take Tekturna HCT. Your healthcare provider may need to monitor you more closely and, in some situations, this medication may not be the best choice for you.
  • Tekturna HCT may affect electrolytes in the blood (including sodium, calcium, potassium, magnesium, and chloride). Therefore, your healthcare provider will regularly check these levels. If you notice any symptoms of an electrolyte imbalance, contact your healthcare provider right away. These symptoms include:
    • Dry mouth
    • Increased thirst
    • Weakness
    • Tiredness
    • Restlessness
    • Seizures
    • Confusion
    • Muscle pain or cramps
    • A decrease in urine output
    • A weak or irregular heartbeat
    • Nausea
    • Vomiting.
  • Hydrochlorothiazide (one of the components of Tekturna HCT) has been reported to worsen systemic lupus erythematosus or, in some cases, to even cause the condition.
  • The hydrochlorothiazide component of Tekturna HCT is also known to worsen gout.
  • Hydrochlorothiazide may cause high blood sugar levels (hyperglycemia) in people with diabetes or, in some cases, even cause diabetes in people without a history of the condition.


  • Drugs that contain hydrochlorothiazide, including this medication, can sometimes cause a potentially dangerous eye reaction (a particularly dangerous type of glaucoma). This reaction usually occurs within days to weeks of starting the drug.

Because this reaction can permanently damage vision, let your healthcare provider know right away if you develop vision changes and/or eye pain. The main treatment for this reaction is to stop taking this medication, although other treatment (including surgery) may sometimes be necessary. 

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Tekturna HCT Drug Information

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