Trandate Drug Interactions (Cont.)

More Detail on Trandate Interactions

 
Cimetidine (Tagamet)
If you are taking Trandate and cimetidine together, your body may metabolize Trandate differently than intended. This interaction can lead to an increased level of Trandate in your body. When using these medicines together, your healthcare provider may choose to monitor you more closely and adjust your Trandate dose as needed.
 
Calcium Channel Blockers
If you are taking Trandate with a calcium channel blocker, your blood pressure may decrease too much or your heart rate may slow dramatically. This can cause symptoms such as a spinning sensation (vertigo), lightheadedness, dizziness, or fainting. You are also at increased risk for developing congestive heart failure. If you are taking a calcium channel blocker and Trandate together, your healthcare provider may choose to monitor your situation more closely and, if necessary, adjust your dose of these medicines.
 
Certain Diabetes Medicines
Taking certain types of diabetes medicines with Trandate may increase the effects of the diabetes medicine, causing blood sugar levels to drop too low (hypoglycemia). If you are taking diabetes medication with Trandate, your healthcare provider may adjust your dosages, monitor you more closely, or both.
 
Tricyclic Antidepressants
People taking Trandate with a tricyclic antidepressant may be at increased risk for tremors. In clinical studies, these tremors were seen in 2.3 percent of people who took Trandate with a tricyclic antidepressant. Your healthcare provider may choose to monitor you more closely and change your medicines if needed.
 
Nitroglycerin
If you are taking Trandate and nitroglycerin together, your body may metabolize these medicines differently than intended. This may cause a drop in blood pressure. Your healthcare provider may choose to monitor you more closely and adjust your dose of either medicine as needed.
 
(Trandate Drug Interactions Continued: Page 3)

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;