Trandate

Trandate is a prescription medication used to control high blood pressure in adults. It belongs to a class of drugs known as beta blockers. While Trandate does not cure high blood pressure, it can significantly lower both diastolic and systolic blood pressure levels. Trandate comes in tablet form and is available in a number of strengths, including 100 mg, 200 mg, and 300 mg. Potential side effects of the medicine may include nausea, fatigue, nasal congestion, and dizziness. Generic versions of Trandate are available.

 

What Is Trandate?

Trandate® (labetalol hydrochloride) is a prescription medicine that has been licensed for controlling high blood pressure (hypertension) in adults. It is not a cure for high blood pressure.
 
Trandate has not been approved for use in children.
 
(Click Trandate Uses for more information on what Trandate is used for, including possible off-label uses of the medication.)
 

Who Makes Trandate?

Trandate is manufactured by Prometheus Laboratories.
 

How Does Trandate Work?

Trandate is part of a class of drugs called beta-adrenergic blocking agents, or beta blockers for short.
 As the name implies, beta blockers block beta receptors in the body. Beta receptors are located in a number of places within the body, including the heart and blood vessels. These receptors are what stress hormones (such as adrenaline) attach to and cause certain reactions in the body, such as an increase in:
 
By blocking beta receptors, Trandate causes the reverse effect of stress hormones. It decreases heart rate and both systolic and diastolic blood pressure, as well as the workload of the heart.
 
Unlike a lot of other beta blockers, Trandate also blocks alpha receptors. The alpha blocker component of Trandate works more on the peripheral blood vessels (arteries and veins), or those blood vessels in the arms and legs. By blocking the alpha receptors, Trandate relaxes these blood vessels.
 
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;