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Specific Drugs That React With Trandolapril-Verapamil ER

Trandolapril-Verapamil ER Interactions Explained

The following sections explain in detail the potentially negative interactions that can occur when trandolapril-verapamil ER is combined with any of the drugs listed above.
 
Aliskiren
Combining trandolapril-verapamil ER with aliskiren may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required. Aliskiren and trandolapril-verapamil ER should never be combined in people with diabetes, because they may have a higher risk for these complications. Also, this combination is not recommended for people with moderate to severe kidney problems.
 
Angiotensin II Receptor Blockers (ARBs)
Combining trandolapril-verapamil ER with an ARB may increase the risk of dangerously low blood pressure (hypotension), fainting, kidney problems (including kidney failure), and dangerously high potassium levels in the blood (hyperkalemia). In general, such combinations are usually avoided. If it is necessary to take such medications together, very close monitoring will be required.
  
Anesthetics
If you will be receiving anesthesia (such as for surgery) make sure your anesthesiologist knows that you are taking trandolapril-verapamil ER, as this may influence the choice and dosage of anesthetics.
 
Beta Blockers
If you are taking trandolapril-verapamil ER and a beta blocker, your blood pressure or heart rate may decrease too much. Your healthcare provider may choose to monitor your progress closely.
 
Carbamazepine
Trandolapril-verapamil ER may increase the level of carbamazepine in the blood, possibly increasing the risk of carbamazepine side effects. Check with your healthcare provider before taking these medications together.
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Trandolapril-Verapamil Hydrochloride ER

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