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Drug Interactions With Valsartan and Hydrochlorothiazide

As with any medication, there are potential drug interactions with valsartan and hydrochlorothiazide. For example, taking it along with a potassium supplement or salt substitute with potassium can cause the levels of potassium in your blood to become too high -- which can cause serious problems. Other interactions can change how your body metabolizes the drugs and make certain drugs less effective.

An Overview of Valsartan and Hydrochlorothiazide Drug Interactions

Valsartan and hydrochlorothiazide (Diovan HCT®) can potentially interact with a number of other medicines. Some of these valsartan and hydrochlorothiazide interactions can include:
  • Alcohol
  • Barbiturates, such as:
    • Amobarbital (Amytal®)
    • Butabarbital (Butisol Sodium®)
    • Phenobarbital (Luminal®)
    • Primidone (Mysoline®)
    • Pentobarbital (Nembutal®)
    • Thiopental (Pentothal®)
  • Potassium supplements or salt substitutes with potassium.
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Valsartan HCT

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