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Dosing Guidelines and Effects of Valsartan and Hydrochlorothiazide

Valsartan and Hydrochlorothiazide Effects

A blood pressure reading consists of two numbers -- for example: 120/80. The top number is known as the systolic blood pressure and the bottom number is the diastolic blood pressure. During clinical studies in people taking valsartan and hydrochlorothiazide, systolic blood pressure (the top number) decreased by 14 to 21 mmHg on average and diastolic blood pressure (the bottom number) decreased by 8 to 11 mmHg on average.
By lowering blood pressure, valsartan and hydrochlorothiazide can decrease the risk of developing health problems, such as a heart attack or stroke, that are caused by long-term high blood pressure (see Effects of High Blood Pressure).

When and How Do I Take Valsartan and Hydrochlorothiazide?

Some general considerations for when and how to take valsartan and hydrochlorothiazide include:
  • Valsartan and hydrochlorothiazide comes in tablet form. It is usually taken once a day.
  • Valsartan and hydrochlorothiazide may be taken with or without food.  


  • Valsartan and hydrochlorothiazide should be taken at the same time each day to maintain an even level of the medication in your blood.
  • For valsartan and hydrochlorothiazide to work properly, you have to take it as prescribed. Valsartan and hydrochlorothiazide will not work if you stop taking it.

Valsartan and Hydrochlorothiazide Dosing

The dose of valsartan and hydrochlorothiazide your healthcare provider recommends will vary depending on a number of factors, including:
  • Other medical conditions you may have
  • Other medications you may currently be taking
  • How you respond to valsartan and hydrochlorothiazide.
As with any medication, do not adjust your valsartan and hydrochlorothiazide dose unless your healthcare provider specifically instructs you to do so.
(Click Valsartan and Hydrochlorothiazide Dosing for more information about dosing guidelines for valsartan and hydrochlorothiazide.)
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