The Risks With Bisoprolol Use During Pregnancy
When given to pregnant rats and rabbits, very high doses of
bisoprolol increased the risk of miscarriages. Bisoprolol did not appear to increase the risk of birth defects. However, it is important to note that animals do not always respond to medicines the same way that humans do. Therefore, a pregnancy Category C medicine may be given to a pregnant woman if a healthcare provider believes that the benefits to the woman outweigh any possible risks to the unborn child.
Little human research has been done on the effects of bisoprolol on the fetus. There is one report of a woman who took bisoprolol (along with a few other medications) during pregnancy. Although the baby had numerous birth defects, this one case does not strongly suggest that there is a link between bisoprolol and birth defects in humans.
With
beta blockers in general, there have been reports of slowed intrauterine growth, small placentas, and birth defects related to their use during pregnancy. There have also been reports of a very low heart rate, low blood sugars, and/or decreased breathing in some newborns whose mothers took beta blockers just before or during childbirth.
Pregnancy and Ziac: Final Thoughts
If you are pregnant or thinking about becoming pregnant, let your healthcare provider know. He or she will consider the benefits and risks of using
Ziac during pregnancy before making a recommendation in your particular situation.
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