Ziac Interactions

If you take certain medications with Ziac, drug interactions could occur. Some of the medicines that may interact with this blood pressure medication include corticosteroids, calcium channel blockers, NSAIDs, and narcotics. These interactions can increase your risk of developing extremely low blood pressure, dangerously slow heart rate, strokes, or other serious problems.

An Overview of Ziac Drug Interactions

 Ziac® (bisoprolol and hydrochlorothiazide) can potentially interact with several other medications. Some of the medicines that may lead to drug interactions with Ziac include:
 
  • Alcohol
  • Barbiturates, such as:
 
    • Amobarbital (Amytal®)
    • Butalbital (Fioricet®, Fiorinal®)
    • Pentobarbital (Nembutal®)
    • Phenobarbital (Luminal®)
    • Secobarbital (Seconal®)
 
 
 
 
 
  • Certain arrhythmia medications, such as:
 
    • Amiodarone (Cordarone®)
    • Disopyramide (Norpace®, Norpace CR®)
    • Lidocaine (Xylocaine®)
    • Propafenone (Rythmol®)
    • Quinidine
    • Sotalol (Betapace®)
 
 
    • Betamethasone (Celestone®)
    • Cortisone
    • Dexamethasone (Decadron®)
    • Fludrocortisone (Florinef®)
    • Hydrocortisone (Cortef®)
    • Methylprednisolone (Depo-Medrol®, Medrol®)
    • Prednisolone (Ovapred®, Pediapred®)
    • Prednisone
    • Triamcinolone (Kenalog®, Aristospan®)
 
 
 
 
 
  • Reserpine
  • Rifampin (Rifadin®).
     

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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;
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