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Irbesartan/HCTZ is a medicine prescribed for the treatment of high blood pressure. The medicine combines two blood pressure medications to achieve its effects, which include reducing blood volume and relaxing the blood vessels. This reduces the workload on the heart and improves blood flow. This medication comes in tablet form and is taken once daily. Side effects can include dizziness, nausea, and tiredness.

What Is Irbesartan/HCTZ?

Irbesartan/HCTZ (Avalide®) is a combination medication used in the treatment of high blood pressure, known medically as hypertension. It combines two high blood pressure medications: irbesartan (Avapro®) and hydrochlorothiazide (Microzide®, Oretic®), or HCTZ for short.
(Click What Is Irbesartan/HCTZ Used For? for more information on this topic, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, irbesartan/HCTZ can cause side effects. However, not everyone who takes the drug will experience problems. In fact, most people tolerate it quite well.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious reactions are less common.
Common side effects of irbesartan/HCTZ include but are not limited to:
  • Dizziness
  • Tiredness
  • Muscle and joint pain
  • Nausea and vomiting.
(Click Side Effects of Irbesartan/HCTZ to learn more, including potentially serious side effects you should report immediately to your healthcare provider.)
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Irbesartan/Hydrochlorothiazide Drug Information

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