Hypertension Home > Cardene SR

Cardene SR is an extended-release medication that is prescribed for treating high blood pressure. By slowing down the rate at which calcium moves into your heart and blood vessel walls, the drug can help relax the blood vessels and improve blood flow. Cardene SR comes in the form of a capsule and is usually taken twice a day. Side effects of the medication may include hot flashes, swelling in the legs or feet, and heart palpitations.

What Is Cardene SR?

Cardene SR® (nicardipine SR) is a prescription medication used to treat high blood pressure (hypertension). Cardene SR capsules are extended release, meaning they slowly release the medication over time.
(Click Cardene SR Uses for more information on what Cardene SR is used for, including possible off-label uses.)

Who Makes Cardene SR?

Cardene SR is made by Hoffmann-La Roche, Inc.

How Does Cardene SR Work?

Cardene SR is part of a class of drugs called calcium channel blockers. Cardene SR helps to slow down the rate at which calcium moves into your heart and blood vessel walls. This, in turn, helps to relax the vessels, which improves blood flow and makes it easier for the heart to pump blood.
There are two basic types of calcium channel blockers, dihydropyridine and non-dihydropyridine. The most important difference between the two types is that non-dihydropyridine calcium channel blockers can slow down the heart rate, while dihydropyridine calcium channel blockers do not. Cardene SR is a dihydropyridine calcium channel blocker, which means that it does not usually decrease the heart rate.

When and How to Take Cardene SR

Some general considerations for when and how to take Cardene SR include:
  • Cardene SR comes in the form of a capsule. Cardene SR is taken by mouth, usually twice a day.
  • It does not matter if you take Cardene SR with or without food.
  • Cardene SR should be taken at the same times each day to maintain an even level of the drug in your blood.
  • For Cardene SR to work properly, it must be taken as prescribed. Cardene SR will not work if you stop taking it.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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