Hypertension Home > Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide

Available by prescription only, olmesartan medoxomil/amlodipine/hydrochlorothiazide is approved for treating high blood pressure. This combination medication helps to lower blood pressure by relaxing the blood vessels, improving the efficiency of the heart, and reducing blood volume. It comes in tablet form and is taken once daily. Possible side effects include swelling, headaches, and dizziness.

What Is Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide?

Olmesartan medoxomil/amlodipine/hydrochlorothiazide (Tribenzor™) is a combination medication used to treat high blood pressure, known medically as hypertension. It contains three blood pressure medications -- olmesartan (Benicar®), amlodipine (Norvasc®), and hydrochlorothiazide.
Olmesartan medoxomil/amlodipine/hydrochlorothiazide may be a good option for people who are already taking two blood pressure medications without adequate blood pressure control. It may also be an option for people who are already taking the individual components as three separate pills and would rather take just one pill. Olmesartan medoxomil/amlodipine/hydrochlorothiazide is not approved for use as the first-choice medication to treat high blood pressure.
(Click What Is Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide Used For? for more information, including possible off-label uses.)

Are There Side Effects?

Just like any medicine, olmesartan medoxomil/amlodipine/hydrochlorothiazide can cause side effects. However, not everyone who uses the drug will experience problems. Most people tolerate it quite well.
Common side effects of olmesartan medoxomil/amlodipine/hydrochlorothiazide include but are not limited to:
  • Dizziness
  • Swelling, or edema, in the hands, ankles, feet, or joints
  • Headaches
  • Tiredness
  • Stuffy or runny nose and sore throat.
If reactions do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. Serious side effects are less common.
(Click Side Effects of Olmesartan Medoxomil/Amlodipine/Hydrochlorothiazide to learn more, including potentially serious side effects that you should report immediately to your healthcare provider.)
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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