Hypertension Home > Trandate

Trandate is commonly used to control high blood pressure in adults. It belongs to a class of drugs known as beta blockers. While the medication does not cure high blood pressure, it can significantly lower both diastolic and systolic blood pressure. Most people have no problems with it, but side effects are possible and may include nausea, fatigue, nasal congestion, and dizziness.

What Is Trandate?

Trandate® (labetalol hydrochloride) is a prescription medicine that has been licensed for controlling high blood pressure (hypertension) in adults. It is not a cure for this condition, however.
This medication has not been approved for use in children.
(Click Trandate Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Trandate is manufactured by Prometheus Laboratories.

How Does It Work?

Trandate is part of a class of drugs called beta-adrenergic blocking agents, or beta blockers for short. As the name implies, beta blockers block beta receptors in the body. Beta receptors are located in a number of places, including the heart and blood vessels. These receptors are what stress hormones such as adrenaline attach to and cause certain reactions in the body, such as an increase in:
By blocking beta receptors, Trandate causes the reverse effect of stress hormones. It decreases heart rate and systolic and diastolic blood pressure, as well as the workload of the heart.
Unlike a lot of other beta blockers, Trandate also blocks alpha receptors. The alpha blocker component works more on the peripheral blood vessels (arteries and veins in the arms and legs). By blocking the alpha receptors, the medication causes these blood vessels to relax.
Written by/reviewed by:
Last reviewed by: Kristi Monson, PharmD;
Last updated/reviewed:
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